Title |
Natural Products to Counteract the Epidemic of Cardiovascular and Metabolic Disorders
|
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Published in |
Molecules, June 2016
|
DOI | 10.3390/molecules21060807 |
Pubmed ID | |
Authors |
Birgit Waltenberger, Andrei Mocan, Karel Šmejkal, Elke H. Heiss, Atanas G. Atanasov |
Abstract |
Natural products have always been exploited to promote health and served as a valuable source for the discovery of new drugs. In this review, the great potential of natural compounds and medicinal plants for the treatment or prevention of cardiovascular and metabolic disorders, global health problems with rising prevalence, is addressed. Special emphasis is laid on natural products for which efficacy and safety have already been proven and which are in clinical trials, as well as on plants used in traditional medicine. Potential benefits from certain dietary habits and dietary constituents, as well as common molecular targets of natural products, are also briefly discussed. A glimpse at the history of statins and biguanides, two prominent representatives of natural products (or their derivatives) in the fight against metabolic disease, is also included. The present review aims to serve as an "opening" of this special issue of Molecules, presenting key historical developments, recent advances, and future perspectives outlining the potential of natural products for prevention or therapy of cardiovascular and metabolic disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 59 | 12% |
India | 29 | 6% |
United Kingdom | 15 | 3% |
Mexico | 12 | 3% |
Canada | 9 | 2% |
France | 6 | 1% |
Venezuela, Bolivarian Republic of | 6 | 1% |
Brazil | 5 | 1% |
Australia | 4 | <1% |
Other | 72 | 15% |
Unknown | 257 | 54% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 397 | 84% |
Scientists | 38 | 8% |
Practitioners (doctors, other healthcare professionals) | 25 | 5% |
Science communicators (journalists, bloggers, editors) | 12 | 3% |
Unknown | 2 | <1% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | <1% |
Mexico | 1 | <1% |
United States | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 192 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 26 | 13% |
Student > Ph. D. Student | 22 | 11% |
Researcher | 18 | 9% |
Student > Master | 12 | 6% |
Student > Postgraduate | 11 | 6% |
Other | 44 | 22% |
Unknown | 63 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Pharmacology, Toxicology and Pharmaceutical Science | 30 | 15% |
Agricultural and Biological Sciences | 19 | 10% |
Biochemistry, Genetics and Molecular Biology | 19 | 10% |
Chemistry | 18 | 9% |
Medicine and Dentistry | 16 | 8% |
Other | 21 | 11% |
Unknown | 73 | 37% |